HYPOSPADIAS
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Little baby boys pass urine like a fountain. Small lads can stand and pass urine straight with an ability to point the stream where they want, like a fire-man’s hose. This is possible because the urine comes out of the opening at the tip of the online pharmacy. In boys with hypospadias, the opening is located on the under surface of penis. Because of this the urine is deviated downwards towards their feet.

How is hypospadias detected?

Hypospadias occurs in one in 300 male newborns. When the paediatrician checks out the baby, or when the parents bath the baby, the following features are there-

  • Abnormal spraying of urine
  • Penis being slightly bent downwards
  • Having to sit down to urinate
  • Malformed foreskin that makes the penis look "hooded"
  • Urethra opening on the underside of the penis
  • What are the consequences of Hypospadias?

When hypospadias is left uncorrected, the following consequences can develop

Hypospadiac lads have to sit; if they stand and pass urine, it goes down the leg.
When they get older, sexual activities become difficult.
Sometimes the urinary opening is also small, leading to blockage in urine stream. This leaves them at a risk of urinary infection.

Do they have other birth defects? Can the same problem recur in future children?

In general, hypospadiac children do not have other kidney abnormalities. However in 10% of these kids, the testis may not be descended normally. When the first child or the father has hypospadias, there is a slightly higher chance (7-10%) for the future boys in the family to have the same birth defect.

What is the right time to correct hypospadias?

From 6 months onwards, hypospadias can be corrected by an operation. Not having an appearance like other boys at school, can lead to emotional problems in these children.

What does the operation involve? What are the complications?

Most of the hypospadias can be operated by a single stage operation. When the opening is too far down from the tip, they might require two-stage operation. The operation is usually done under general anesthesia and a catheter/ dressing is left for 5-7 days. Three things are corrected during the operation.

  • The opening is brought to the tip
  • The penis is straightened
  • Excess foreskin is removed (circumcision).
  • Optical magnification (microscope) and fine suture materials are essential for a successful result. When extra care is taken there is a very good (95%) success rate. In 5% the following complications can occur.

The new opening gets small gradually (meatal stenosis)
Urine leaks at the original site (Fistula)
Both these can be corrected by another minor operation; so the parents need not have undue concern about this.

What are the chances of fertility after operation?

Straight penis and an opening at the tip are essential for a successful married life and fertility. When the problem is corrected by 1-3 years of age with a good outcome, there should be no problem in future for fertility.

Key Points:

1. In children with hypospadias, the opening is on the under surface of penis.
2. Because of this, these lads can’t stand and pass urine like normal children.
3. They can have infertility in later life, if left uncorrected.
4. By performing a corrective surgery at the right age, these can be avoided.


Another Reason to Avoid Prescription Drugs Whenever Possible
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Drinking water contains traces of nine drugs, new study finds

The Vancouver Sun 2004

Sarah Staples
CanWest News Service

Saturday, November 13, 2004

The federal government's first study of pharmaceuticals in drinking water will confirm traces of common painkillers, anti-cholesterol drugs and the antidepressant Prozac are ending up in the treated water that Canadians drink, CanWest News Service has learned.

A study by researchers from the National Water Research Institute for Health and Environment Canada, designed to gauge how efficiently plants removed traces of drugs from drinking water, found nine different drugs in water samples taken near 20 drinking water treatment plants across southern Ontario.

The drugs were mainly from a class known as "acidic pharmaceuticals," and included the painkillers ibuprofen and neproxin, and gemfibrozil, a cholesterol-lowering viagra. Concentrations were in the parts per trillion -- comparable to one cent in $10 billion. "Barely detectable" levels of Prozac were also found.

The worst contamination came from treatment plants located near rivers or downstream from sewage treatment plants, as opposed to those plants sourcing water from lakes or groundwater.

The study has been submitted to the British scientific journal Water Research and is expected to be published sometime in the New Year.

While the amounts are well below prescription doses, experts from the NWRI say confirmation of even scant levels of a burgeoning assortment of drugs in Canada's drinking water is a troubling find warranting further investigation.

"It's kind of a brand new ball game and we don't know enough," said Jim Maguire, director of the institute's aquatic ecosystem protection research branch.

Residues of hormones are well known to disrupt the reproductive abilities of amphibians and fish. There is also suspicion that antibiotic residues working their way up the food chain may promote resistance to the drugs, while many other medications could harm fetuses, and people who are ill or infirm.

The effects of pesticides are better understood and regulated in Canada than personal care products, such as lotions and cosmetics, or prescription pharmaceuticals, said Maguire.

"You need to know how long lasting [the contamination is], and if it's being continually reintroduced -- but there's no country in the world that has enough information," he said. "We're kind of like where we were 25 years ago with PCBs and dioxides."

The government study is the first official acknowledgement of long-standing suspicions voiced by Canada's water-quality experts.

Transcripts obtained by CanWest News Service of a Health Canada-sponsored international workshop in 2002 show government chemists voicing serious concern over the possible negative effects of trace pharmaceuticals, at a time when U.S. and European studies were starting to reveal antibiotics and chemotherapeutics, drugs for epilepsy and depression, anti-inflammatory drugs, veterinary drugs, fragrances such as musk, and hormones in treated sewage runoff and tap water.

Informal private testing carried out last year on behalf of media outlets revealed residues of gemfibrozil and the anticonvulsant drug carbamazepine in tap water from towns and cities across Canada.

The federal government isn't testing for the full range of drugs that could be in Canada's potable water supply, preferring initially to limit its search to "acidic" drugs because they are easiest to spot using existing pesticide analysis techniques, said Kent Burnison, an NWRI microbiologist who co-wrote the study.

Ontario's water was surveyed not because of any special concern over its safety, but because samples had to be taken near NWRI's laboratory to preserve their integrity, he said.

The United States and Europe -- which acknowledged pharmaceutical accumulation several years before Canada began studying the phenomenon -- have already begun releasing the first disturbing results of experiments to understand the impact of drugs in the water on fish and wildlife.

In October, for example, the U.S. Geological Survey and the Department of Environmental Protection, revealed 42 to 79 per cent of the male smallmouth bass from a section of the Potomac River known to harbour nicotine-related chemicals and caffeine traces have started producing eggs.

Studies in Colorado waterways recently encountered more examples of "intersex" males, as well as female fish that are having trouble reproducing.

The working hypothesis is that leftover estrogen from chicken droppings or human hormones, not traditional pollutants from agriculture or mining, are disrupting the fish's reproduction.

In Europe and Japan, scientists are turning their attention to devising ways of cleaning drinking water using new, hypersensitive nano-scale filtration materials.

Burnison's lab is in the midst of a multi-year study of the environmental impacts of the drugs found so far in Canada's drinking water.

With a growing and aging population of baby boomers who will rely increasingly on cheap cialis, water experts fear the problem may only get worse.

"You may prove that individual pharmaceuticals aren't doing that much [to the environment], but when you've got a 100 or more compounds together, what is the synergistic effect?" he said.

"Is it one plus one equals two, or does it equal three and four?"

FOUND IN THE WATER

Detectable levels of many common drugs have been found in Canadian drinking water.

- Analgesics ibuprofen and neproxin.

- Antidepressant Prozac.

- Anti-cholesterol medication gemfibrozil.

- Anticonvulsant drug carbamazepine.

- Traces of nicotine, caffeine and estrogen are detectable in some wildlife.

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I Got Nothing
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I'm a day behind, and so I should be writing two blog posts today in order to catch up.

But really. I got nothing.

Usually, I have something to complain about. Or I can walk you through my day, and spit out a thousand words that way. Today, I had the day off, and I mostly laid around in bed watching movies, reading, resting. It was fabulous, I assure you, but not a day I feel compelled to blog about. I suppose I could write a mini-thesis on the superiority of watching television in bed versus watching television while sitting on the couch, but I suspect you have your own Best Way, and my way is just my way. I could give you a review of The Girlfriend Experience, but if you want the tepid reviews, you can read them on Amazon. I could tell you everything I like about Christopher Eccleston as the Ninth Doctor, and the total cuteness/yummy-ness of Billie Piper, but fangirl squee makes for boring blogging.

I've been cruising around Googling "freelance writing" this evening. There's an amusingly vast number of "how to" articles written no doubt by freelance writers trying to generate web content, about freelancers generating web content. If you're not careful, you could fall into one of these black holes and lose every shred of hope you ever had of making a living as a writer. There are several websites that purport to list useful leads for freelancers, mostly for copywriters who can work in person, in SoHo, generating ad copy for the myriad of uninteresting products and services that require dull and uninspiring internet ad copy. I'm reminded of a million monkeys on a million typewriters, and also a documentary I saw about people in some Asian country living in internet cafes, making a dollar per webpage or some sad statistic like that, no doubt writing Nigerian e-mail scams and cialis spam. Maybe writing code that spontaneously generates Nigerian e-mail scams and cialis spam.

Freelance writing just doesn't seem to be a viable career. It seems sort of like eating celery, where you burn more calories chewing than you actually gain from digesting. And in the end, you have a portfolio full of badly spelled Nigerian e-mail scams and invitations to watch Mandy on LiveWebCam. It's what you do, I suppose, when you Got Nothing. Sort of like what I have today. I don't have any bright ideas for a new poem, short story, or novel. I don't have any bright ideas about brilliant blog posts. I checked my stats today, and the Top 10 Western Dumplings post is my current best-seller. It seems that a lot of people are seeking photographs of spaetzle and soup dumplings. My stats tracker says I should be blogging about unusual foods, not the existential angst of making a living as a writer. I should definitely NOT be posting poetry, or stories from my trunk. I should not be doing book reviews, especially if the books are several years old. Movies out in theaters now seem to be an ok draw. Perhaps that's it. I write about a movie and a weird food, every day.

I could give you a behind-the-scenes on the movie-theater hopping I wrote about the other day. When my friend and I used to spend the day at the movies, slinking from theater to theater, we would first make a food run. I had a huge, black, fake leather purse, and we'd make the rounds at our favorites places to fill the sucker up before seeing the first matinee. Candy. Sodas and chips. Loaded baked potatoes from Wendy's. With chili and cheese and sour cream. Red vines. All loaded into this great big shoulder bag and smuggled into the theater. There were many days when we were the only people in the theater, and we would unpack this disgusting picnic and make pigs of ourselves in the light of the silver screen. We'd eat enough calories to fuel an entire third world village, and wash it down with cold Coca Cola. Little did I know back then that I would be recounting the story in a desperate attempt to Have Something, when I Got Nothing.

This article about freelancing showed up on my Facebook wall today. Among other things, it says that you can't be a writer and have writer's block. You need to be able to sit down and generate copy on demand. You don't have time to be a prima donna. You have to put words on the page in order to eat. However uninspired. However awful and pointless. You have to make the words flow in order to live. If you have to beat yourself about the head and shoulders with a tire iron. If you stay up too late. If you piss everybody off. If you bore everyone to tears. You have to Have Something, because if you've Got Nothing, you'll starve. In a gutter. Without pants. And die.

So, even if I've Got Nothing, I'll write about that.

I'll write about anything. Even nothing at all.


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